SCHEMBL940552

SCHEMBL940552

Cl[SiH2]C(C1CCCCC1)C1CCCCC1

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 2/20 0.38
SHBG P04278 1/20 0.38
TP53 P04637 1/20 0.35
ALDH1A1 P00352 1/20 0.33
HSD17B10 Q99714 1/20 0.33
KDM4E B2RXH2 1/20 0.33
GMNN O75496 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
BLM P54132 1/20 0.33
PMP22 Q01453 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5032261 0.97 EPHX1 (0.33) EPHX1SHBGTP53
SCHEMBL619888 0.83
SCHEMBL9011820 0.75 SHBG (0.39) EPHX1SHBGTP53KDM4EGMNN
SCHEMBL8955976 0.69 EPHX1 (0.40) EPHX1SHBGTP53ALDH1A1HSD17B10
SCHEMBL8955301 0.69 EPHX1 (0.40) EPHX1SHBGTP53ALDH1A1HSD17B10
SCHEMBL8955223 0.69 EPHX1 (0.40) EPHX1SHBGTP53ALDH1A1HSD17B10
SCHEMBL9331170 0.69 EPHX1 (0.40) EPHX1SHBGTP53ALDH1A1HSD17B10
SCHEMBL5031098 0.67 EPHX1 (0.48) EPHX1SHBGTP53ALDH1A1KDM4E
Cyclohexane SCHEMBL2027488 0.67 EPHX1 (0.41) EPHX1SHBGTP53ALDH1A1HSD17B10
Cyclohexane SCHEMBL3485509 0.67 EPHX1 (0.41) EPHX1SHBGTP53ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009582-A1 Preparation of Activating Supports TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2011-01-13 US claimed
EP-2170511-A1 PREPARATION OF ACTIVATING SUPPORTS Total Petrochemicals Research Feluy (BE) 2010-04-07 EP claimed
WO-2009013197-A1 PREPARATION OF ACTIVATING SUPPORTS TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2009-01-29 WO claimed
CN-103391947-B Stabilization of polymers containing hydrolyzable functional groups 株式会社普利司通 2016-08-24 CN disclosed
CN-103068884-B Photosensitive silicone resin composition ASAHI KASEI E MATERIALS CORP 2015-06-17 CN disclosed
US-20130158148-A1 PHOTOSENSITIVE SILICONE RESIN COMPOSITION ASAHI KASEI E-MATERIALS CORPORATION (JP) 2013-06-20 US disclosed
EP-2604644-A1 PHOTOSENSITIVE SILICONE RESIN COMPOSITION Asahi Kasei E-Materials Corporation (JP) 2013-06-19 EP disclosed
US-8394737-B2 Preparation of activating supports TOTAL PETROCHEMICALS RESEARCH FELUY Seneffe (BE) 2013-03-12 US disclosed
US-20110009582-A1 Preparation of Activating Supports TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2011-01-13 US disclosed
EP-2170511-A1 PREPARATION OF ACTIVATING SUPPORTS Total Petrochemicals Research Feluy (BE) 2010-04-07 EP disclosed
WO-2009013197-A1 PREPARATION OF ACTIVATING SUPPORTS TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2009-01-29 WO disclosed
EP-0542499-B1 Thermal disproportionation of cycloalkylsilanes DOW CORNING (US) 1997-06-04 EP disclosed
EP-0549226-B1 Sodium borohydride catalyzed disproportionation of cycloorganosilanes DOW CORNING (US) 1997-04-02 EP disclosed
EP-0534700-B1 Process for cycloalkyl substitution of hydrogen containing silanes DOW CORNING (US) 1996-11-20 EP disclosed
EP-0549226-A1 Sodium borohydride catalyzed disproportionation of cycloorganosilanes DOW CORNING CORPORATION (US) 1993-06-30 EP disclosed
EP-0542499-A1 Thermal disproportionation of cycloalkylsilanes DOW CORNING CORPORATION (US) 1993-05-19 EP disclosed
EP-0534700-A1 Process for cycloalkyl substitution of hydrogen containing silanes DOW CORNING CORPORATION (US) 1993-03-31 EP disclosed
US-5136070-A Sodium borohydride catalyzed disproportionation of cycloorganosilanes DOW CORNING CORPORATION (US) 1992-08-04 US disclosed
US-5126471-A Cycloalkyldihalosilanes to dicycloalkyldihalosilanes DOW CORNING CORPORATION (US) 1992-06-30 US disclosed
US-5118829-A Organoborane compound catalyst DOW CORNING CORPORATION (US) 1992-06-02 US disclosed