Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 4/20 | 0.50 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.50 |
| ▸ | XIAP | P98170 | 13/20 | 0.48 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9405617 | 1.00 | GHSR (0.50) | GHSRAGTR1XIAPMMEACE | |
| SCHEMBL9024283 | 0.90 | XIAP (0.54) | GHSRAGTR1XIAPMMEACE | |
| SCHEMBL9024929 | 0.89 | GHSR (0.55) | GHSRAGTR1XIAP | |
| SCHEMBL9405556 | 0.88 | GHSR (0.56) | GHSRAGTR1XIAP | |
| SCHEMBL9405704 | 0.87 | GHSR (0.55) | GHSRAGTR1XIAP | |
| SCHEMBL9025303 | 0.86 | XIAP (0.58) | GHSRAGTR1XIAP | |
| SCHEMBL9405558 | 0.86 | XIAP (0.58) | GHSRAGTR1XIAP | |
| SCHEMBL9405628 | 0.86 | XIAP (0.53) | GHSRAGTR1XIAP | |
| SCHEMBL9405613 | 0.86 | GHSR (0.48) | GHSRAGTR1XIAPACE | |
| SCHEMBL9024272 | 0.85 | GHSR (0.53) | GHSRAGTR1XIAPMMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5310737-A | Benzo-fused lactams that promote the release of growth hormone | MERCK & CO., INC. (US) | 1994-05-10 | — | — | US | disclosed |
| US-5206235-A | Animal growth regulators; stimulants | MERCK & CO., INC. (US) | 1993-04-27 | — | — | US | disclosed |
| WO-1992016524-A1 | BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO., INC. (US) | 1992-10-01 | — | — | WO | disclosed |