Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 12/20 | 0.35 |
| ▸ | CNR1 | P21554 | 8/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | CEL | P19835 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9405961 | 1.00 | RIPK1 (0.38) | RIPK1CNR2CNR1SLC6A2SLC6A4 | |
| SCHEMBL9406008 | 0.99 | RIPK1 (0.37) | RIPK1CNR2CNR1SLC6A2SLC6A4 | |
| SCHEMBL9405779 | 0.99 | RIPK1 (0.37) | RIPK1CNR2CNR1SLC6A2SLC6A4 | |
| SCHEMBL9405775 | 0.99 | RIPK1 (0.37) | RIPK1CNR2CNR1SLC6A2SLC6A4 | |
| SCHEMBL9406004 | 0.99 | RIPK1 (0.37) | RIPK1CNR2CNR1SLC6A2SLC6A4 | |
| SCHEMBL9405787 | 0.99 | RIPK1 (0.37) | RIPK1CNR2CNR1SLC6A2SLC6A4 | |
| SCHEMBL9405791 | 0.99 | RIPK1 (0.37) | RIPK1CNR2CNR1SLC6A2SLC6A4 | |
| SCHEMBL9405667 | 0.97 | RIPK1 (0.38) | RIPK1CNR2CNR1SLC6A2SLC6A4 | |
| SCHEMBL9405669 | 0.97 | RIPK1 (0.38) | RIPK1CNR2CNR1SLC6A2SLC6A4 | |
| SCHEMBL10429849 | 0.96 | RIPK1 (0.36) | RIPK1CNR2CNR1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5279764-A | Dihalogenobenzene derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-01-18 | — | — | US | disclosed |