Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RARB | P10826 | 9/20 | 0.44 |
| ▸ | RARA | P10276 | 2/20 | 0.44 |
| ▸ | RARG | P13631 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9406238 | 1.00 | HSD17B10 (0.44) | HSD17B10TSHRRARBRARARARG | |
| SCHEMBL9406057 | 1.00 | HSD17B10 (0.44) | HSD17B10TSHRRARBRARARARG | |
| SCHEMBL9405882 | 0.99 | MAPT (0.43) | HSD17B10TSHRRARBRARARARG | |
| SCHEMBL9406582 | 0.94 | RARB (0.41) | HSD17B10TSHRRARBRARARARG | |
| SCHEMBL12735556 | 0.91 | RARB (0.42) | HSD17B10TSHRRARBRARARARG | |
| SCHEMBL12740093 | 0.91 | RARB (0.42) | HSD17B10TSHRRARBRARARARG | |
| SCHEMBL10091369 | 0.91 | RARB (0.42) | HSD17B10TSHRRARBRARARARG | |
| SCHEMBL9406154 | 0.89 | GABRA1 (0.40) | HSD17B10MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL10301921 | 0.88 | RARB (0.39) | HSD17B10TSHRRARBRARARARG | |
| SCHEMBL13235363 | 0.88 | MAPT (0.40) | HSD17B10TSHRRARBRARARARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5279764-A | Dihalogenobenzene derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-01-18 | — | — | US | disclosed |