Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | TLR4 | O00206 | 1/20 | 0.30 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9406055 | 1.00 | RIPK1 (0.38) | RIPK1CTSLCTSSCTSKHTR2A | |
| SCHEMBL9924983 | 0.96 | RIPK1 (0.36) | RIPK1CTSLCTSSCTSKHTR2A | |
| SCHEMBL19160558 | 0.96 | RIPK1 (0.40) | RIPK1CTSLCTSSCTSKHTR2A | |
| SCHEMBL9630395 | 0.95 | RIPK1 (0.38) | RIPK1CTSLCTSSCTSKHTR2A | |
| SCHEMBL9630399 | 0.95 | RIPK1 (0.38) | RIPK1CTSLCTSSCTSKHTR2A | |
| SCHEMBL9924827 | 0.93 | HTR2A (0.33) | RIPK1CTSLCTSSCTSKHTR2A | |
| SCHEMBL9924893 | 0.93 | SCN9A (0.34) | RIPK1CTSLCTSSCTSKHTR2A | |
| SCHEMBL9924779 | 0.93 | SCN9A (0.34) | RIPK1CTSLCTSSCTSKHTR2A | |
| SCHEMBL9925054 | 0.93 | HTR2A (0.33) | RIPK1CTSLCTSSCTSKHTR2A | |
| SCHEMBL9405759 | 0.93 | RIPK1 (0.36) | RIPK1HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5279764-A | Dihalogenobenzene derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-01-18 | — | — | US | disclosed |