Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 7/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9406277 | 0.93 | RARB (0.47) | RARBMAPTALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL9406402 | 0.93 | RARB (0.47) | RARBMAPTALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL9405773 | 0.93 | RARB (0.47) | RARBMAPTALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL9405854 | 0.93 | RARB (0.47) | RARBMAPTALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL9406129 | 0.92 | RARB (0.46) | RARBMAPTALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL9405691 | 0.92 | RARB (0.46) | RARBMAPTALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL9405972 | 0.90 | RARB (0.57) | RARBMAPTALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL7515625 | 0.84 | RARB (0.40) | RARBMAPTALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL7513581 | 0.84 | RARB (0.40) | RARBMAPTALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL7520463 | 0.84 | RARB (0.40) | RARBMAPTALDH1A1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5279764-A | Dihalogenobenzene derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-01-18 | — | — | US | disclosed |