Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 9/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MPL | P40238 | 2/20 | 0.38 |
| ▸ | RARA | P10276 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9405682 | 0.94 | RARB (0.55) | RARBRAB9AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL9406137 | 0.94 | RARB (0.55) | RARBRAB9AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL9406131 | 0.94 | RARB (0.55) | RARBRAB9AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL9342525 | 0.94 | RARB (0.55) | RARBRAB9AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL9405879 | 0.93 | RARB (0.54) | RARBRAB9AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL9406333 | 0.93 | RARB (0.54) | RARBRAB9AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL9406196 | 0.90 | RARB (0.49) | RARBRAB9AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL9341872 | 0.85 | MAPT (0.58) | RARBRAB9AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL17551841 | 0.84 | RARB (0.52) | RARBMAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL9406114 | 0.83 | RARB (0.52) | RARBRAB9AMAPTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5279764-A | Dihalogenobenzene derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-01-18 | — | — | US | disclosed |