Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9406407 | 1.00 | KMT2A (0.42) | KMT2AMEN1L3MBTL1RAB9AHPGD | |
| SCHEMBL9562711 | 0.94 | POLB (0.45) | KMT2AMEN1L3MBTL1RAB9AHPGD | |
| SCHEMBL9562707 | 0.94 | POLB (0.45) | KMT2AMEN1L3MBTL1RAB9AHPGD | |
| SCHEMBL9562350 | 0.94 | HPGD (0.46) | KMT2AMEN1L3MBTL1RAB9AHPGD | |
| SCHEMBL9562353 | 0.94 | HPGD (0.46) | KMT2AMEN1L3MBTL1RAB9AHPGD | |
| SCHEMBL9562686 | 0.91 | HPGD (0.43) | KMT2AMEN1L3MBTL1RAB9AHPGD | |
| SCHEMBL9562374 | 0.91 | POLB (0.45) | KMT2AMEN1L3MBTL1RAB9AHPGD | |
| SCHEMBL9562338 | 0.91 | HPGD (0.39) | KMT2AMEN1L3MBTL1RAB9AHPGD | |
| SCHEMBL9562340 | 0.91 | HPGD (0.39) | KMT2AMEN1L3MBTL1RAB9AHPGD | |
| SCHEMBL9562372 | 0.91 | POLB (0.45) | KMT2AMEN1L3MBTL1RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5279764-A | Dihalogenobenzene derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-01-18 | — | — | US | disclosed |