Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9191329 | 1.00 | MEN1 (0.37) | MEN1KMT2AHTTCNR1CNR2 | |
| SCHEMBL9562608 | 0.98 | MEN1 (0.37) | MEN1KMT2AHTTCNR1CNR2 | |
| SCHEMBL9562612 | 0.98 | MEN1 (0.37) | MEN1KMT2AHTTCNR1CNR2 | |
| SCHEMBL9561958 | 0.97 | MEN1 (0.37) | MEN1KMT2AHTTCNR1CNR2 | |
| SCHEMBL9561959 | 0.97 | MEN1 (0.37) | MEN1KMT2AHTTCNR1CNR2 | |
| SCHEMBL9562705 | 0.97 | GAA (0.37) | MEN1KMT2AHTTCNR1CNR2 | |
| SCHEMBL9562698 | 0.97 | GAA (0.37) | MEN1KMT2AHTTCNR1CNR2 | |
| SCHEMBL9405685 | 0.97 | MEN1 (0.39) | MEN1KMT2AHTTCNR1CNR2 | |
| SCHEMBL9406330 | 0.97 | MEN1 (0.39) | MEN1KMT2AHTTCNR1CNR2 | |
| SCHEMBL9406016 | 0.97 | MEN1 (0.39) | MEN1KMT2AHTTCNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5279764-A | Dihalogenobenzene derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-01-18 | — | — | US | disclosed |
| US-5248447-A | 2,3-difluorohydroquinone derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-09-28 | — | — | US | disclosed |