Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9562705 | 1.00 | GAA (0.37) | GAAMAPTNPC1PTGESALOX5 | |
| SCHEMBL9562612 | 0.99 | MEN1 (0.37) | GAAMAPTNPC1PTGESALOX5 | |
| SCHEMBL9562608 | 0.99 | MEN1 (0.37) | GAAMAPTNPC1PTGESALOX5 | |
| SCHEMBL9406470 | 0.97 | MEN1 (0.37) | GAAMAPTNPC1PKMMEN1 | |
| SCHEMBL9191329 | 0.97 | MEN1 (0.37) | GAAMAPTNPC1PKMMEN1 | |
| SCHEMBL9562557 | 0.97 | GAA (0.37) | GAAMAPTNPC1PTGESALOX5 | |
| SCHEMBL9562564 | 0.97 | GAA (0.37) | GAAMAPTNPC1PTGESALOX5 | |
| SCHEMBL9562619 | 0.97 | MAPT (0.40) | GAAMAPTNPC1PTGESALOX5 | |
| SCHEMBL9562616 | 0.97 | MAPT (0.40) | GAAMAPTNPC1PTGESALOX5 | |
| SCHEMBL9405748 | 0.97 | GAA (0.39) | GAAMAPTNPC1PTGESALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5248447-A | 2,3-difluorohydroquinone derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-09-28 | — | — | US | claimed |
| US-5248447-A | 2,3-difluorohydroquinone derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-09-28 | — | — | US | disclosed |
| EP-0332007-B1 | DERIVATIVES OF 2,3-DIFLUOROHYDROQUINONE | MERCK PATENT GmbH (DE) | 1992-11-25 | — | — | EP | disclosed |
| EP-0373186-A1 | DERIVATIVES OF 2,3-DIFLUOROHYDROQUINONE | MERCK PATENT GmbH (DE) | 1990-06-20 | — | — | EP | disclosed |
| WO-1989008637-A1 | DERIVATIVES OF 2,3-DIFLUOROHYDROQUINONE | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1989-09-21 | — | — | WO | disclosed |