Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 11/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.54 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.53 |
| ▸ | PPARD | Q03181 | 7/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | LCK | P06239 | 1/20 | 0.52 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.52 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 6/20 | 0.50 |
| ▸ | PPARA | Q07869 | 6/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TLR2 | O60603 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | FABP4 | P15090 | 2/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9498760 | 1.00 | GPR84 (0.67) | GPR84LMNAFFAR1FFAR4PPARD | |
| SCHEMBL10438736 | 1.00 | GPR84 (0.67) | GPR84LMNAFFAR1FFAR4PPARD | |
| SCHEMBL9500437 | 1.00 | GPR84 (0.67) | GPR84LMNAFFAR1FFAR4PPARD | |
| SCHEMBL5074106 | 1.00 | GPR84 (0.67) | GPR84LMNAFFAR1FFAR4PPARD | |
| SCHEMBL9498754 | 1.00 | GPR84 (0.67) | GPR84LMNAFFAR1FFAR4PPARD | |
| SCHEMBL23879500 | 1.00 | GPR84 (0.67) | GPR84LMNAFFAR1FFAR4PPARD | |
| SCHEMBL2307490 | 1.00 | GPR84 (0.67) | GPR84LMNAFFAR1FFAR4PPARD | |
| SCHEMBL22404400 | 1.00 | GPR84 (0.67) | GPR84LMNAFFAR1FFAR4PPARD | |
| SCHEMBL22404039 | 1.00 | GPR84 (0.67) | GPR84LMNAFFAR1FFAR4PPARD | |
| SCHEMBL8981724 | 1.00 | GPR84 (0.67) | GPR84LMNAFFAR1FFAR4PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5278300-A | Pharmaceuticals with immunopotentiation, antitumor, mitogenic, tumor necrosis factor-inducing, interferon-inducing activity; low toxicity | JAPAN TOBACCO, INC. (JP) | 1994-01-11 | — | — | US | disclosed |
| US-5191072-A | Drugs, antitumor | JAPAN TOBACCO INC. (JP) | 1993-03-02 | — | — | US | disclosed |