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Zinc Ion

Zinc Ion

SCHEMBL940723

Cc1cccc(N(C(=S)[S-])c2cccc(C)c2C)c1C.Cc1cccc(N(C(=S)[S-])c2cccc(C)c2C)c1C.[Zn+2]

nearest known ligand 0.40

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 2/20 0.40
▸ TRPA1 O75762 1/20 0.39
▸ ATM Q13315 1/20 0.39
▸ ALDH1A1 P00352 7/20 0.37
▸ KMT2A Q03164 2/20 0.36
▸ LMNA P02545 2/20 0.36
▸ MEN1 O00255 1/20 0.36
▸ TSHR P16473 1/20 0.34
▸ MAPK1 P28482 1/20 0.34
▸ SMN1; SMN2 Q16637 1/20 0.34
▸ GAA P10253 3/20 0.33
▸ NPSR1 Q6W5P4 1/20 0.33
▸ ESR1 P03372 1/20 0.33
▸ ESR2 Q92731 1/20 0.33
▸ CA12 O43570 1/20 0.33
▸ CA1 P00915 1/20 0.33
▸ CA2 P00918 1/20 0.33
▸ CA9 Q16790 1/20 0.33
▸ GLA P06280 1/20 0.33
▸ HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16628403 0.96 MAPT (0.40) MAPTTRPA1ATMALDH1A1KMT2A
Potassium Ion SCHEMBL16628482 0.96 MAPT (0.40) MAPTTRPA1ATMALDH1A1KMT2A
SCHEMBL16628443 0.96 MAPT (0.40) MAPTTRPA1ATMALDH1A1KMT2A
SCHEMBL16628410 0.96 MAPT (0.40) MAPTTRPA1ATMALDH1A1KMT2A
SCHEMBL4391190 0.96 MAPT (0.40) MAPTTRPA1ATMALDH1A1KMT2A
Zinc Ion SCHEMBL941335 0.84 CA12 (0.39) MAPTALDH1A1LMNATSHRMAPK1
SCHEMBL16628602 0.80 CA12 (0.39) MAPTALDH1A1LMNATSHRGAA
Lithium Ion SCHEMBL9355801 0.80 CA12 (0.39) MAPTALDH1A1LMNATSHRGAA
SCHEMBL9355683 0.80 CA12 (0.44) MAPTALDH1A1LMNATSHRGAA
SCHEMBL16628430 0.80 CA12 (0.39) MAPTALDH1A1LMNATSHRGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1570034-B1 UREA GREASE COMPOSITION SHELL INT RESEARCH (NL) 2016-02-17 — — EP disclosed
EP-1639063-B1 Use of a Grease Composition SHELL INT RESEARCH (NL) 2014-06-25 — — EP disclosed
EP-1831338-B1 UREA-BASED LUBRICATING GREASE COMPOSITION SHELL INT RESEARCH (NL) 2012-06-13 — — EP disclosed
US-7867956-B2 Urea-based lubricating grease composition SHELL OIL COMPANY (US) 2011-01-11 — — US disclosed
US-7629301-B2 Mixture of oil, urea thickener agent, molybdenum or zinc dithio(carbamate or phosphate) and metal salt of fatty acid SHOWA SHELL SEKIYU K.K. (JP) 2009-12-08 — — US disclosed
US-20080161214-A1 Urea-Based Lubricating Grease Composition SHELL OIL COMPANY (US) 2008-07-03 — — US disclosed
EP-1831338-A1 UREA-BASED LUBRICATING GREASE COMPOSITION Shell Internationale Research Maatschappij B.V. (NL) 2007-09-12 — — EP disclosed
WO-2006069986-A1 UREA-BASED LUBRICATING GREASE COMPOSITION SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 2006-07-06 — — WO disclosed
EP-1639063-A1 GREASE COMPOSITION SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 2006-03-29 — — EP disclosed
EP-1570034-A1 UREA GREASE COMPOSITION SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 2005-09-07 — — EP disclosed
US-20050003970-A1 Grease composition SHOWA SHELL SEKIYU K.K. (JP) 2005-01-06 — — US disclosed
WO-2004113481-A1 GREASE COMPOSITION SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 2004-12-29 — — WO disclosed
US-20040224859-A1 low noise and high lubricity; mixture of diurea compounds and zinc or molybdenum dithiophosphates or dithiocarbonates; synergistic effects of such S-P type additives with the urea thickening agents SHELL OIL COMPANY 2004-11-11 — — US disclosed
WO-2004053032-A1 UREA GREASE COMPOSITION SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 2004-06-24 — — WO disclosed