Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9355683 | 0.96 | CA12 (0.44) | CA12CA1CA2CA9TSHR | |
| Zinc Ion SCHEMBL941335 | 0.96 | CA12 (0.39) | CA12CA1CA2CA9TSHR | |
| SCHEMBL4386453 | 0.96 | CA12 (0.39) | CA12CA1CA2CA9TSHR | |
| SCHEMBL16628430 | 0.96 | CA12 (0.39) | CA12CA1CA2CA9TSHR | |
| Potassium Ion SCHEMBL9356020 | 0.96 | CA12 (0.39) | CA12CA1CA2CA9TSHR | |
| Lithium Ion SCHEMBL9355801 | 0.96 | CA12 (0.39) | CA12CA1CA2CA9TSHR | |
| SCHEMBL16628410 | 0.84 | MAPT (0.40) | CA12CA1CA2CA9TSHR | |
| Potassium Ion SCHEMBL16628482 | 0.80 | MAPT (0.40) | CA12CA1CA2CA9TSHR | |
| SCHEMBL16628403 | 0.80 | MAPT (0.40) | CA12CA1CA2CA9TSHR | |
| SCHEMBL4391190 | 0.80 | MAPT (0.40) | CA12CA1CA2CA9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2860170-B1 | PROCESS FOR PREPARING 4-HYDROXYBUTYL ACRYLATE | OSAKA ORGANIC CHEMICAL IND LTD (JP) | 2019-08-28 | — | — | EP | disclosed |
| US-9670129-B2 | Process for preparing 4-hydroxybutyl acrylate | OSAKA ORGANIC CHEMICAL INDUSTRY LTD. (JP) | 2017-06-06 | — | — | US | disclosed |
| US-20150126766-A1 | PROCESS FOR PREPARING 4-HYDROXYBUTYL ACRYLATE | OSAKA ORGANIC CHEMICAL INDUSTRY LTD. (JP) | 2015-05-07 | — | — | US | disclosed |
| EP-2860170-A1 | PROCESS FOR PREPARING 4-HYDROXYBUTYL ACRYLATE | Osaka Organic Chemical Ind., Ltd. (JP) | 2015-04-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150126766-A1 | PROCESS FOR PREPARING 4-HYDROXYBUTYL ACRYLATE | LTB4R2, LTA4H, LTB4R | CA12 4614/4885CA1 4540/4885CA2 4547/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.