SCHEMBL9407407

SCHEMBL9407407

CC(C)(C)[Si](OC[C@@H]1CCC(n2ccc(=O)[nH]c2=O)O1)(c1ccccc1)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
DUT P33316 8/20 0.46
SMYD2 Q9NRG4 3/20 0.39
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
BCHE P06276 1/20 0.36
NT5E P21589 1/20 0.35
ABL1 P00519 1/20 0.35
RIN1 Q13671 1/20 0.35
P2RY2 P41231 2/20 0.34
P2RY12 Q9H244 1/20 0.34
P2RY14 Q15391 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9129024 1.00 DUT (0.46) DUTSMYD2MEN1KMT2ABCHE
SCHEMBL9129020 1.00 DUT (0.46) DUTSMYD2MEN1KMT2ABCHE
SCHEMBL18480441 0.88 DUT (0.45) DUTSMYD2MEN1KMT2ANT5E
SCHEMBL22110474 0.86 DUT (0.61) DUTMEN1KMT2ABCHEP2RY2
SCHEMBL22666041 0.86 DUT (0.61) DUTMEN1KMT2ABCHEP2RY2
SCHEMBL25374524 0.86 BCHE (0.50) BCHE
SCHEMBL9126280 0.86 BCHE (0.50) BCHE
SCHEMBL9126273 0.86 BCHE (0.50) BCHE
SCHEMBL30481508 0.86 BCHE (0.50) BCHE
SCHEMBL15941862 0.82 DUT (0.46) DUTSMYD2NT5EP2RY2P2RY12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0598910-A1 PROCESS FOR PRODUCING NUCLEOSIDE DERIVATIVE Japan Tobacco Inc. (JP) 1994-06-01 EP disclosed