SCHEMBL9407484

SCHEMBL9407484

CCCCNCCC(C)NCCCC

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.48
ALDH1A1 P00352 2/20 0.48
ADH1B P00325 2/20 0.38
ADH1C P00326 2/20 0.38
ADH1A P07327 2/20 0.38
ADH7 P40394 2/20 0.38
ADH4 P08319 1/20 0.38
CYP2C19 P33261 2/20 0.36
MEN1 O00255 1/20 0.36
GLA P06280 1/20 0.36
KMT2A Q03164 1/20 0.36
CALM1 P0DP23 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.33
ADRB2 P07550 4/20 0.33
SIGMAR1 Q99720 1/20 0.33
S1PR2 O95136 2/20 0.32
S1PR4 O95977 2/20 0.32
S1PR1 P21453 2/20 0.32
S1PR3 Q99500 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11750018 0.91 TSHR (0.56) TSHRALDH1A1ADH1BADH1CADH1A
SCHEMBL10045197 0.91 TSHR (0.56) TSHRALDH1A1ADH1BADH1CADH1A
SCHEMBL10045265 0.91 TSHR (0.42) TSHRALDH1A1ADH1BADH1CADH1A
SCHEMBL10045248 0.90 TSHR (0.44) TSHRALDH1A1ADH1BADH1CADH1A
SCHEMBL7775148 0.87 TSHR (0.39) TSHRALDH1A1ADH1BADH1CADH1A
SCHEMBL24075866 0.87 TDP1 (0.46) TSHRALDH1A1ADH1BADH1CADH1A
SCHEMBL10045149 0.86 CYP2C19 (0.42) TSHRALDH1A1ADH1BADH1CADH1A
SCHEMBL10045198 0.86 TSHR (0.50) TSHRALDH1A1ADH1BADH1CADH1A
Hydrochloric Acid SCHEMBL22575458 0.85 TSHR (0.38) TSHRALDH1A1ADH1BADH1CADH1A
SCHEMBL28726709 0.85 ADRB2 (0.42) TSHRALDH1A1ADH1BADH1CADH1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0590419-A1 Process for preparing unsaturated amines BASF Aktiengesellschaft (DE) 1994-04-06 EP disclosed