Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3068694 | 0.90 | SMN1; SMN2 (0.47) | SMN1; SMN2TP53KMT2AMEN1CYP3A4 | |
| SCHEMBL9407564 | 0.87 | IDO1 (0.41) | SMN1; SMN2TP53KMT2AMEN1CYP3A4 | |
| SCHEMBL9407550 | 0.85 | CKS1B (0.38) | SMN1; SMN2TP53HDAC3HDAC1HDAC2 | |
| SCHEMBL9407513 | 0.83 | SMN1; SMN2 (0.43) | SMN1; SMN2KMT2AMEN1IDO1MAPT | |
| SCHEMBL9363322 | 0.82 | TDP1 (0.49) | SMN1; SMN2KMT2AMEN1CYP3A4CYP2C9 | |
| SCHEMBL15283620 | 0.80 | CKS1B (0.50) | SMN1; SMN2KMT2AMEN1CYP3A4CYP2C9 | |
| SCHEMBL27572033 | 0.80 | TP53 (0.54) | SMN1; SMN2TP53HDAC3HDAC1HDAC2 | |
| SCHEMBL15189256 | 0.80 | NPC1 (0.52) | SMN1; SMN2TP53KMT2AMEN1CYP3A4 | |
| SCHEMBL3061972 | 0.79 | NPC1 (0.46) | SMN1; SMN2TP53HDAC3HDAC4HDAC1 | |
| SCHEMBL5090319 | 0.78 | MEN1 (0.50) | SMN1; SMN2TP53HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0610943-A1 | Pyridinium derivatives useful as PAF antagonists | J. URIACH & CIA. S.A. (ES) | 1994-08-17 | — | — | EP | disclosed |