Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 4/20 | 0.41 |
| ▸ | CKS1B | P61024 | 1/20 | 0.39 |
| ▸ | SKP1 | P63208 | 1/20 | 0.39 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9407493 | 0.87 | SMN1; SMN2 (0.48) | IDO1F2CKS1BSKP1SKP2 | |
| SCHEMBL9407550 | 0.82 | CKS1B (0.38) | IDO1F2CKS1BSKP1SKP2 | |
| SCHEMBL6636248 | 0.80 | F2 (0.47) | F2SMN1; SMN2MEN1KMT2ACYP3A4 | |
| SCHEMBL9407513 | 0.80 | SMN1; SMN2 (0.43) | IDO1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL3068694 | 0.80 | SMN1; SMN2 (0.47) | IDO1CKS1BSKP1SKP2SMN1; SMN2 | |
| SCHEMBL9363322 | 0.79 | TDP1 (0.49) | IDO1F2CKS1BSKP1SKP2 | |
| SCHEMBL15189256 | 0.79 | NPC1 (0.52) | IDO1CKS1BSKP1SKP2SMN1; SMN2 | |
| SCHEMBL5107520 | 0.79 | SMN1; SMN2 (0.47) | F2SMN1; SMN2MEN1KMT2ACYP3A4 | |
| SCHEMBL15283620 | 0.77 | CKS1B (0.50) | IDO1CKS1BSKP1SKP2SMN1; SMN2 | |
| SCHEMBL5090319 | 0.76 | MEN1 (0.50) | F2SMN1; SMN2MEN1KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0610943-A1 | Pyridinium derivatives useful as PAF antagonists | J. URIACH & CIA. S.A. (ES) | 1994-08-17 | — | — | EP | disclosed |