Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 6/20 | 0.69 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | THPO | P40225 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9407515 | 0.89 | GPBAR1 (0.65) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL12046916 | 0.82 | CYSLTR1 (0.77) | CYSLTR1GPBAR1KDM4EMEN1NPC1 | |
| SCHEMBL30444017 | 0.82 | CYSLTR1 (1.00) | CYSLTR1GPBAR1KDM4EMEN1NPC1 | |
| SCHEMBL422355 | 0.82 | CYSLTR1 (1.00) | CYSLTR1GPBAR1KDM4EMEN1NPC1 | |
| Hydrochloric Acid SCHEMBL7006935 | 0.81 | CYSLTR1 (0.97) | CYSLTR1GPBAR1KDM4EMEN1NPC1 | |
| SCHEMBL10632491 | 0.78 | CYSLTR1 (0.78) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL9407498 | 0.78 | ALOX5 (0.59) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL9407556 | 0.78 | CYSLTR1 (0.57) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL9130463 | 0.78 | CYSLTR1 (1.00) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL7014302 | 0.78 | CYSLTR1 (0.63) | CYSLTR1GPBAR1KDM4EMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0610943-A1 | Pyridinium derivatives useful as PAF antagonists | J. URIACH & CIA. S.A. (ES) | 1994-08-17 | — | — | EP | disclosed |