Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | PRCP | P42785 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 3/20 | 0.36 |
| ▸ | HTR2C | P28335 | 3/20 | 0.36 |
| ▸ | HRH1 | P35367 | 3/20 | 0.36 |
| ▸ | HTR2B | P41595 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9407786 | 1.00 | CHRM3 (0.37) | CHRM3CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL9407790 | 1.00 | CHRM3 (0.37) | CHRM3CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL9407788 | 1.00 | CHRM3 (0.37) | CHRM3CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL9407831 | 0.99 | CHRM3 (0.38) | CHRM3CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL9407828 | 0.99 | CHRM3 (0.38) | CHRM3CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL9407832 | 0.99 | CHRM3 (0.38) | CHRM3CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL9585536 | 0.80 | GRIN2B (0.41) | GRIN2BMEN1HTR2AHTR2CHRH1 | |
| SCHEMBL9585532 | 0.80 | GRIN2B (0.41) | GRIN2BMEN1HTR2AHTR2CHRH1 | |
| SCHEMBL9407787 | 0.78 | DRD2 (0.36) | CHRM3CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL9407792 | 0.78 | DRD2 (0.36) | CHRM3CHRM2CHRM4CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0601249-A1 | Benzocycloheptene derivative and process for preparation thereof | TANABE SEIYAKU CO., LTD. (JP) | 1994-06-15 | — | — | EP | disclosed |
| US-5252589-A | Inhibits contraction of urinary bladder | TANABE SEIKAYU CO., LTD. (JP) | 1993-10-12 | — | — | US | disclosed |