Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28016314 | 0.80 | TDP1 (0.51) | TDP1LMNAMAPTALDH1A1MAPK1 | |
| SCHEMBL304176 | 0.78 | TDP1 (0.78) | TDP1LMNAMAPTALDH1A1MAPK1 | |
| SCHEMBL20224967 | 0.78 | TDP1 (0.58) | TDP1LMNAMAPTALDH1A1MAPK1 | |
| SCHEMBL28207503 | 0.77 | TDP1 (0.75) | TDP1LMNAMAPTALDH1A1MAPK1 | |
| Bicarbonate SCHEMBL7699565 | 0.77 | TDP1 (0.75) | TDP1LMNAMAPTALDH1A1MAPK1 | |
| Ammonia Solution, Strong SCHEMBL28588274 | 0.77 | TDP1 (0.75) | TDP1LMNAMAPTALDH1A1MAPK1 | |
| SCHEMBL26023562 | 0.76 | MAPT (0.68) | TDP1LMNAMAPTALDH1A1L3MBTL1 | |
| SCHEMBL305162 | 0.76 | MAPT (0.68) | TDP1LMNAMAPTALDH1A1L3MBTL1 | |
| SCHEMBL27995933 | 0.76 | L3MBTL1 (0.48) | TDP1LMNAMAPTALDH1A1L3MBTL1 | |
| SCHEMBL13950834 | 0.76 | TDP1 (0.55) | TDP1LMNAMAPTALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0602524-A1 | Chemiluminescence marked sequences and their use in sequence testing | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-06-22 | — | — | EP | disclosed |