Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | P2RY14 | Q15391 | 5/20 | 0.37 |
| ▸ | LIPE | Q05469 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | DRD5 | P21918 | 4/20 | 0.36 |
| ▸ | DRD1 | P21728 | 3/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9408325 | 0.96 | HTR2C (0.41) | HTR2CHSD11B1NOTUMP2RY14LIPE | |
| SCHEMBL9408387 | 0.85 | DPP4 (0.39) | NOTUM | |
| SCHEMBL9408367 | 0.83 | HRH3 (0.38) | P2RY14PDE2APDE5ATEAD1 | |
| SCHEMBL9408359 | 0.82 | HDAC2 (0.37) | KIF11TGM2 | |
| SCHEMBL9408307 | 0.82 | MAPT (0.41) | HSD11B1 | |
| SCHEMBL9408246 | 0.82 | NPC1 (0.36) | P2RY14LIPEADRA1BDRD3PDE2A | |
| SCHEMBL9408252 | 0.82 | NPC1 (0.36) | P2RY14LIPEADRA1BDRD3PDE2A | |
| SCHEMBL9408288 | 0.81 | DPP4 (0.37) | SLC6A3 | |
| SCHEMBL9408407 | 0.81 | HTR2C (0.41) | HTR2CP2RY14LIPEKIF11TEAD1 | |
| SCHEMBL9408348 | 0.80 | HRH3 (0.37) | P2RY14PDE2APDE5ATEAD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0595144-A1 | Cyclohexyl alkenoates as components of liquid crystalline mixtures | F. HOFFMANN-LA ROCHE AG (CH) | 1994-05-04 | — | — | EP | disclosed |