Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | USP5 | P45974 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 2/20 | 0.32 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9408387 | 0.96 | DPP4 (0.39) | DPP4DPP8DPP9ALDH1A1SMN1; SMN2 | |
| SCHEMBL9408253 | 0.86 | HDAC2 (0.35) | ALDH1A1USP5NPC1RAB9AHDAC4 | |
| SCHEMBL9408293 | 0.86 | NPC1 (0.34) | SMN1; SMN2CCR1USP5NPC1RAB9A | |
| SCHEMBL9408302 | 0.86 | NPC1 (0.34) | SMN1; SMN2CCR1USP5NPC1RAB9A | |
| SCHEMBL9408244 | 0.86 | BCL2L1 (0.39) | CCR1MEN1KMT2A | |
| SCHEMBL9408325 | 0.86 | HTR2C (0.41) | SLC6A3 | |
| SCHEMBL9408471 | 0.86 | USP5 (0.38) | CCR1USP5CCR2APP | |
| SCHEMBL9408350 | 0.84 | IDO1 (0.44) | ALDH1A1ATM | |
| SCHEMBL9408190 | 0.83 | MAPT (0.35) | ALDH1A1SMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL9408378 | 0.83 | GRIA1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0595144-A1 | Cyclohexyl alkenoates as components of liquid crystalline mixtures | F. HOFFMANN-LA ROCHE AG (CH) | 1994-05-04 | — | — | EP | disclosed |