Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9408374 | 1.00 | ALDH1A1 (0.41) | ALDH1A1MAPTSMN1; SMN2HSD11B1KDM4E | |
| SCHEMBL9408426 | 0.96 | ALDH1A1 (0.39) | ALDH1A1MAPTSMN1; SMN2HSD11B1KDM4E | |
| SCHEMBL9408436 | 0.96 | ALDH1A1 (0.39) | ALDH1A1MAPTSMN1; SMN2HSD11B1KDM4E | |
| SCHEMBL9408252 | 0.85 | NPC1 (0.36) | ALDH1A1MAPTSMN1; SMN2DRD2LMNA | |
| SCHEMBL9408246 | 0.85 | NPC1 (0.36) | ALDH1A1MAPTSMN1; SMN2DRD2LMNA | |
| SCHEMBL9408217 | 0.84 | IDO1 (0.47) | ALDH1A1TSHR | |
| SCHEMBL9408367 | 0.83 | HRH3 (0.38) | KMT2AMEN1L3MBTL1 | |
| SCHEMBL9408359 | 0.82 | HDAC2 (0.37) | ALDH1A1MAPTLMNALDHAL3MBTL1 | |
| SCHEMBL9408307 | 0.82 | MAPT (0.41) | MAPTHSD11B1LMNAHPGDHIF1A | |
| SCHEMBL9408387 | 0.82 | DPP4 (0.39) | ALDH1A1SMN1; SMN2KDM4EDRD2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0595144-A1 | Cyclohexyl alkenoates as components of liquid crystalline mixtures | F. HOFFMANN-LA ROCHE AG (CH) | 1994-05-04 | — | — | EP | disclosed |