Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.42 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.42 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.38 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.37 |
| ▸ | EP300 | Q09472 | 2/20 | 0.34 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.34 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | FASN | P49327 | 2/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9408388 | 1.00 | GRIA1 (0.42) | GRIA1GRIA2GRIA3HSD11B1USP30 | |
| SCHEMBL9408211 | 0.96 | GRIA1 (0.44) | GRIA1GRIA2GRIA3HSD11B1USP30 | |
| SCHEMBL9408206 | 0.96 | GRIA1 (0.44) | GRIA1GRIA2GRIA3HSD11B1USP30 | |
| SCHEMBL9408293 | 0.83 | NPC1 (0.34) | P2RY14 | |
| SCHEMBL9408302 | 0.83 | NPC1 (0.34) | P2RY14 | |
| SCHEMBL9408288 | 0.83 | DPP4 (0.37) | — | |
| SCHEMBL9408244 | 0.83 | BCL2L1 (0.39) | HSD11B1 | |
| SCHEMBL9408253 | 0.83 | HDAC2 (0.35) | — | |
| SCHEMBL9408337 | 0.82 | GRIA1 (0.42) | GRIA1GRIA2GRIA3HSD11B1USP30 | |
| SCHEMBL9408329 | 0.82 | GRIA1 (0.42) | GRIA1GRIA2GRIA3HSD11B1USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0595144-A1 | Cyclohexyl alkenoates as components of liquid crystalline mixtures | F. HOFFMANN-LA ROCHE AG (CH) | 1994-05-04 | — | — | EP | disclosed |