Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | SMURF2 | Q9HAU4 | 1/20 | 0.33 |
| ▸ | SMURF1 | Q9HCE7 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.32 |
| ▸ | USP5 | P45974 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9408358 | 0.96 | USP5 (0.32) | GPR139PPARGPPARAPANK3APP | |
| SCHEMBL9408419 | 0.88 | USP5 (0.38) | APPUSP5HDAC6 | |
| SCHEMBL9408471 | 0.85 | USP5 (0.38) | APPUSP5HDAC6 | |
| SCHEMBL9408194 | 0.85 | KDM1A (0.38) | APP | |
| SCHEMBL9408209 | 0.82 | KDM1A (0.40) | PANK3 | |
| SCHEMBL9408184 | 0.82 | KDM1A (0.35) | APPUSP5HDAC6 | |
| SCHEMBL9408208 | 0.82 | PPARG (0.34) | GPR139PPARGPPARAPANK3APP | |
| SCHEMBL9408307 | 0.81 | MAPT (0.41) | HSD11B1 | |
| SCHEMBL9408387 | 0.81 | DPP4 (0.39) | APP | |
| SCHEMBL9408309 | 0.79 | USP5 (0.33) | GPR139PPARGPPARAPANK3MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0595144-A1 | Cyclohexyl alkenoates as components of liquid crystalline mixtures | F. HOFFMANN-LA ROCHE AG (CH) | 1994-05-04 | — | — | EP | disclosed |