Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP5 | P45974 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.31 |
| ▸ | CCR1 | P32246 | 1/20 | 0.31 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9408419 | 0.96 | USP5 (0.38) | USP5HDAC6USP30APPDGAT1 | |
| SCHEMBL9408184 | 0.89 | KDM1A (0.35) | USP5HDAC6APPKDM1A | |
| SCHEMBL9408358 | 0.89 | USP5 (0.32) | USP5HDAC6APP | |
| SCHEMBL9408224 | 0.86 | KDM1A (0.39) | KDM1A | |
| SCHEMBL9408288 | 0.86 | DPP4 (0.37) | USP5APPCCR2CCR1 | |
| SCHEMBL9408441 | 0.85 | GPR139 (0.33) | USP5HDAC6APP | |
| SCHEMBL9408194 | 0.85 | KDM1A (0.38) | APPACMSDKDM1A | |
| SCHEMBL9408244 | 0.83 | BCL2L1 (0.39) | CCR1 | |
| SCHEMBL9408209 | 0.82 | KDM1A (0.40) | USP30KDM1A | |
| SCHEMBL9408328 | 0.82 | USP5 (0.39) | USP5HDAC6USP30APPDGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0595144-A1 | Cyclohexyl alkenoates as components of liquid crystalline mixtures | F. HOFFMANN-LA ROCHE AG (CH) | 1994-05-04 | — | — | EP | disclosed |