Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CCR9 | P51686 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20592414 | 0.90 | NPC1 (0.39) | NPC1RAB9AATMKDM4EMAPT | |
| SCHEMBL19119905 | 0.89 | NPC1 (0.39) | NPC1RAB9AATMKDM4EMAPT | |
| SCHEMBL28641188 | 0.89 | NPC1 (0.39) | NPC1RAB9AATMKDM4EMAPT | |
| SCHEMBL9408834 | 0.86 | NPC1 (0.45) | NPC1RAB9AATMKDM4EMAPT | |
| SCHEMBL9408785 | 0.84 | NPC1 (0.52) | NPC1RAB9AATMKDM4EMAPT | |
| SCHEMBL20591060 | 0.84 | NPC1 (0.40) | NPC1RAB9AATMKDM4EMAPT | |
| SCHEMBL5809113 | 0.84 | NPC1 (0.45) | NPC1RAB9AATMKDM4EMAPT | |
| SCHEMBL29814540 | 0.84 | NPC1 (0.45) | NPC1RAB9AATMKDM4EMAPT | |
| SCHEMBL9408770 | 0.83 | EPHX2 (0.36) | NPC1RAB9AMAPTCYP2C19CYP1A2 | |
| SCHEMBL29349567 | 0.83 | NPC1 (0.41) | NPC1RAB9AATMKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0593936-A1 | N-[2-hydroxy-3-(2H-benzotriazol-2-yl)benzyl]oxamides as light stabilisers | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1994-04-27 | — | — | EP | disclosed |