SCHEMBL9408905

SCHEMBL9408905

CCCCCC[C@@H](O)C/C=C\CCCCCC(C(C)=O)C(C(C)=O)(C(C)=O)C(=O)OC(=O)C(O)CO

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.48
FFAR4 Q5NUL3 1/20 0.48
FAAH O00519 4/20 0.43
DGKA P23743 1/20 0.40
NFKB1 P19838 1/20 0.39
NFKB2 Q00653 1/20 0.39
RELA Q04206 1/20 0.39
TRPV1 Q8NER1 1/20 0.36
PRKCA P17252 2/20 0.35
PRKCE Q02156 1/20 0.34
PRKCQ Q04759 1/20 0.34
PRKCD Q05655 1/20 0.34
DEGS1 O15121 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27580015 0.87 DGKA (0.51) FFAR1FFAR4FAAHDGKANFKB1
SCHEMBL629459 0.87 DGKA (0.51) FFAR1FFAR4FAAHDGKANFKB1
SCHEMBL3092911 0.86 FFAR1 (0.50) FFAR1FFAR4FAAHDGKANFKB1
SCHEMBL6246359 0.82 FFAR1 (0.61) FFAR1FFAR4FAAHNFKB1NFKB2
SCHEMBL873312 0.81 FFAR1 (0.54) FFAR1FFAR4FAAHDGKANFKB1
SCHEMBL9717218 0.80 DGKA (0.56) FFAR1FFAR4FAAHDGKATRPV1
SCHEMBL15686 0.79 FFAR1 (0.63) FFAR1FFAR4FAAHDGKANFKB1
SCHEMBL2120986 0.79 FFAR1 (0.63) FFAR1FFAR4FAAHDGKANFKB1
SCHEMBL6464382 0.79 DGKA (0.42) FFAR1FFAR4FAAHDGKANFKB1
Propene SCHEMBL22734254 0.75 FFAR1 (0.58) FFAR1FFAR4FAAHDGKANFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0455373-A1 Nail enamels containing glyceryl triesters Revlon Consumer Products Corporation (US) 1991-11-06 EP claimed
EP-0613676-A2 Nail enamels containing citrate esters Revlon Consumer Products Corporation (US) 1994-09-07 EP disclosed
EP-0613677-A2 Nail enamels containing triol or glycol esters Revlon Consumer Products Corporation (US) 1994-09-07 EP disclosed
US-5227155-A Film former, solvent and plasticizer REVLON CONSUMER PRODUCTS CORPORATION (US) 1993-07-13 US disclosed
US-5225185-A Plasticizer REVLON CONSUMER PRODUCTS CORPORATION (US) 1993-07-06 US disclosed
US-5145670-A As plasticizing component; formaldehyde free; wear resistance REVLON, INC. (US) 1992-09-08 US disclosed
US-5145671-A As plasticizers REVLON, INC. (US) 1992-09-08 US disclosed
US-5066484-A NAIL ENAMELS CONTAINING GLYCERYL, GLYCOL OR CITRATE ESTERS REVLON, INC. (US) 1991-11-19 US disclosed
EP-0455373-A1 Nail enamels containing glyceryl triesters Revlon Consumer Products Corporation (US) 1991-11-06 EP disclosed