Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.37 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9408904 | 1.00 | KDM4E (0.53) | KDM4ETSHRHPGDHSD17B10GAA | |
| SCHEMBL10671006 | 0.83 | KDM4E (0.53) | KDM4ETSHRHPGDHSD17B10GAA | |
| SCHEMBL3626955 | 0.83 | KDM4E (0.53) | KDM4ETSHRHPGDHSD17B10GAA | |
| SCHEMBL29072360 | 0.81 | KDM4E (0.56) | KDM4ETSHRHPGDHSD17B10GAA | |
| SCHEMBL29072362 | 0.81 | KDM4E (0.56) | KDM4ETSHRHPGDHSD17B10GAA | |
| SCHEMBL3618684 | 0.79 | KDM4E (0.56) | KDM4ETSHRHPGDHSD17B10GAA | |
| SCHEMBL7977837 | 0.76 | GAA (0.47) | KDM4ETSHRHPGDHSD17B10GAA | |
| SCHEMBL10722506 | 0.73 | MAPT (0.55) | KDM4EHPGDGAALMNAALDH1A1 | |
| SCHEMBL5618066 | 0.73 | MAPT (0.46) | KDM4EHPGDHSD17B10GAALMNA | |
| SCHEMBL6206235 | 0.72 | TSHR (0.61) | KDM4ETSHRHPGDHSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016079522-A1 | ANDROGEN RECEPTOR MODULATORS AND THEIR USE AS ANTI-CANCER AGENTS | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 2016-05-26 | — | — | WO | disclosed |
| WO-2016079521-A1 | ANDROGEN RECEPTOR MODULATORS AND THEIR USE AS ANTI-CANCER AGENTS | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 2016-05-26 | — | — | WO | disclosed |
| US-20150057452-A1 | SELECTIVE ANDROGEN RECEPTOR MODULATORS | CATYLIX, INC. (US) | 2015-02-26 | — | — | US | disclosed |
| EP-2834216-A1 | SELECTIVE ANDROGEN RECEPTOR MODULATORS | Catylix Inc. (US) | 2015-02-11 | — | — | EP | disclosed |
| WO-2013152170-A1 | SELECTIVE ANDROGEN RECEPTOR MODULATORS | CATYLIX, INC. (US) | 2013-10-10 | — | — | WO | disclosed |
| EP-0623601-A1 | N-(3-Fluorobenzyl)heterocyclic derivatives and their use as pesticides | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1994-11-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150057452-A1 | SELECTIVE ANDROGEN RECEPTOR MODULATORS | AR, FSHR, NR5A1 | KDM4E 551/4885TSHR 229/4885HPGD 3839/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.