Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | STS | P08842 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1207110 | 0.88 | KDM4E (0.46) | EPHX1PKMPTPN2PTPN1PTPN6 | |
| SCHEMBL9236151 | 0.86 | HPGD (0.53) | EPHX2EPHX1PKMPTPN2PTPN1 | |
| Hydrochloric Acid SCHEMBL9409489 | 0.84 | POLB (0.43) | PKMLMNAPOLBMEN1KMT2A | |
| SCHEMBL9409578 | 0.81 | SMN1; SMN2 (0.40) | EPHX2EPHX1POLBKMT2AL3MBTL1 | |
| SCHEMBL594491 | 0.80 | KDM4E (0.51) | EPHX1PKMPTPN2PTPN1PTPN6 | |
| SCHEMBL1514783 | 0.80 | EPHX1 (0.64) | EPHX2EPHX1PTPN2PTPN1PTPN6 | |
| SCHEMBL9231469 | 0.77 | HPGD (0.54) | EPHX2EPHX1PKMPTPN2PTPN1 | |
| SCHEMBL28577157 | 0.76 | KDM4E (0.47) | EPHX2EPHX1PKMPTPN2PTPN1 | |
| SCHEMBL10177908 | 0.76 | HPGD (0.54) | EPHX1PTPN2PTPN1PTPN6KMT2A | |
| SCHEMBL1437840 | 0.75 | EPHX1 (0.74) | EPHX2EPHX1PTPN2PTPN1PTPN6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0604800-A1 | 4- 4- 4-(carboxyalkyl)-phenyl amino carbonyl -phenyl -piperedines as aggregation inhibitors | Dr. Karl Thomae GmbH (DE) | 1994-07-06 | — | — | EP | disclosed |