Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.42 |
| ▸ | STS | P08842 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9231469 | 0.90 | HPGD (0.54) | HPGDRECQLEPHX2EPHX1PTPN2 | |
| SCHEMBL9409402 | 0.86 | EPHX2 (0.45) | HPGDRECQLEPHX2EPHX1PTPN2 | |
| SCHEMBL594491 | 0.84 | KDM4E (0.51) | HPGDRECQLEPHX1PTPN2PTPN1 | |
| SCHEMBL9237519 | 0.82 | HPGD (0.51) | HPGDRECQLEPHX2EPHX1PTPN2 | |
| SCHEMBL1514783 | 0.81 | EPHX1 (0.64) | HPGDRECQLEPHX2EPHX1PTPN2 | |
| Trifluoroacetic Acid SCHEMBL9237994 | 0.80 | POLB (0.40) | EPHX2 | |
| SCHEMBL28577157 | 0.79 | KDM4E (0.47) | HPGDRECQLEPHX2EPHX1PTPN2 | |
| SCHEMBL7928638 | 0.78 | KDM4E (0.45) | HPGDRECQLEPHX1ALDH1A1KDM4E | |
| SCHEMBL1609547 | 0.78 | EPHX1 (0.59) | HPGDRECQLEPHX2EPHX1PTPN2 | |
| SCHEMBL3771276 | 0.78 | EPHX1 (0.59) | HPGDRECQLEPHX2EPHX1PTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0638553-A1 | Carboxylic acid amides having a terminal carboxylic acid group as aggregation inhibiting drugs | Dr. Karl Thomae GmbH (DE) | 1995-02-15 | — | — | EP | disclosed |