Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.56 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | NAMPT | P43490 | 2/20 | 0.39 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 7/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9409480 | 0.91 | ITGB3 (0.61) | ITGB3ITGA2BLMNAGAANAMPT | |
| SCHEMBL9409478 | 0.85 | ITGB3 (0.45) | ITGB3ITGA2BLMNAGAANAMPT | |
| SCHEMBL9409440 | 0.80 | ITGB3 (0.56) | ITGB3ITGA2BLMNAF10MAPT | |
| Hydrochloric Acid SCHEMBL9409431 | 0.77 | ITGB3 (0.46) | ITGB3ITGA2BNAMPTCYP46A1F10 | |
| SCHEMBL7402980 | 0.75 | ITGB3 (0.50) | ITGB3ITGA2BF10 | |
| SCHEMBL7402982 | 0.75 | ITGB3 (0.50) | ITGB3ITGA2BF10 | |
| SCHEMBL7400796 | 0.75 | ITGB3 (0.51) | ITGB3ITGA2BNAMPTF10 | |
| SCHEMBL7400379 | 0.75 | ITGB3 (0.51) | ITGB3ITGA2BALDH1A1KDM4EMAPT | |
| SCHEMBL8604265 | 0.74 | ITGB3 (0.56) | ITGB3ITGA2BF10 | |
| SCHEMBL8603352 | 0.74 | ITGB3 (0.58) | ITGB3ITGA2BF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0604800-A1 | 4- 4- 4-(carboxyalkyl)-phenyl amino carbonyl -phenyl -piperedines as aggregation inhibitors | Dr. Karl Thomae GmbH (DE) | 1994-07-06 | — | — | EP | disclosed |