Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKZF2 | Q9UKS7 | 3/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 9/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.42 |
| ▸ | ITGA2 | P17301 | 4/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9409660 | 1.00 | IKZF2 (0.44) | IKZF2ITGB3ITGA2BITGA2HDAC4 | |
| Hydrochloric Acid SCHEMBL9409587 | 0.99 | IKZF2 (0.43) | IKZF2ITGB3ITGA2BITGA2HDAC4 | |
| Hydrochloric Acid SCHEMBL9409626 | 0.91 | ITGB3 (0.47) | IKZF2ITGB3ITGA2BITGA2PARP1 | |
| Hydrochloric Acid SCHEMBL9409357 | 0.88 | IKZF2 (0.42) | IKZF2ITGB3ITGA2BITGA2HDAC4 | |
| Hydrochloric Acid SCHEMBL9409577 | 0.87 | IKZF2 (0.45) | IKZF2HDAC4MAOAIKZF1HTR6 | |
| Hydrochloric Acid SCHEMBL9409488 | 0.86 | IKZF2 (0.41) | IKZF2ITGB3ITGA2BHDAC4MAOA | |
| Hydrochloric Acid SCHEMBL9409579 | 0.83 | ITGB3 (0.42) | IKZF2ITGB3ITGA2BITGA2HTR6 | |
| Hydrochloric Acid SCHEMBL9409533 | 0.80 | ITGB3 (0.41) | IKZF2ITGB3ITGA2BITGA2HDAC4 | |
| SCHEMBL23880766 | 0.75 | PARP1 (0.47) | IKZF2PARP1HTR6 | |
| SCHEMBL31482759 | 0.75 | PARP1 (0.47) | IKZF2PARP1HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0604800-A1 | 4- 4- 4-(carboxyalkyl)-phenyl amino carbonyl -phenyl -piperedines as aggregation inhibitors | Dr. Karl Thomae GmbH (DE) | 1994-07-06 | — | — | EP | disclosed |