SCHEMBL9409751

SCHEMBL9409751

O=C(CBr)c1cc(C(=O)CBr)c(C(=O)CBr)cc1C(=O)CBr

nearest known ligand 0.46

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 7/20 0.46
GSK3B P49841 14/20 0.46
HPGDS O60760 1/20 0.39
TSHR P16473 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9409747 0.78 PTPN1 (0.55) PTPN1GSK3BHPGDS
SCHEMBL9409754 0.77 PTPN1 (0.65) PTPN1GSK3BHPGDSTSHR
SCHEMBL6543881 0.75 GSK3B (0.59) PTPN1GSK3BTSHR
SCHEMBL22359915 0.75 GSK3B (0.48) PTPN1GSK3B
SCHEMBL2096480 0.75 PTPN1 (0.43) PTPN1GSK3BHPGDS
SCHEMBL31105825 0.71 HSP90AB1 (0.66) PTPN1TSHR
SCHEMBL3854857 0.71 CA12 (0.57) PTPN1TSHR
SCHEMBL30040752 0.71 GSK3B (0.52) PTPN1GSK3B
SCHEMBL3844607 0.71 HSP90AB1 (0.66) PTPN1TSHR
SCHEMBL4984920 0.71 GSK3B (0.41) PTPN1GSK3BHPGDS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0620500-A2 Resist and pattern formation using the same HITACHI, LTD. (JP) 1994-10-19 EP claimed
EP-0620500-A2 Resist and pattern formation using the same HITACHI, LTD. (JP) 1994-10-19 EP disclosed