SCHEMBL9409747

SCHEMBL9409747

O=C(CBr)c1ccc(C(=O)CBr)c(C(=O)CBr)c1

nearest known ligand 0.55

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 7/20 0.55
GSK3B P49841 13/20 0.54
HPGDS O60760 1/20 0.40
GNG2 P59768 1/20 0.39
GNB1 P62873 1/20 0.39
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL205280 0.78 GSK3B (0.80) PTPN1GSK3B
SCHEMBL9409751 0.78 PTPN1 (0.46) PTPN1GSK3BHPGDS
SCHEMBL11482012 0.77 PTPN1 (0.84) PTPN1GSK3B
SCHEMBL3947199 0.76 PTPN1 (0.52) PTPN1GSK3BMEN1KMT2A
SCHEMBL16056966 0.76 GSK3B (0.55) PTPN1GSK3BGNG2GNB1
SCHEMBL10071769 0.76 PTPN1 (0.57) PTPN1GSK3BGNG2GNB1
SCHEMBL1809513 0.75 PTPN1 (0.50) PTPN1GSK3B
SCHEMBL18398130 0.75 GSK3B (0.53) PTPN1GSK3B
SCHEMBL11634692 0.75 GSK3B (0.50) PTPN1GSK3BGNG2GNB1
SCHEMBL3871906 0.75 GSK3B (0.53) PTPN1GSK3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0620500-A2 Resist and pattern formation using the same HITACHI, LTD. (JP) 1994-10-19 EP claimed
EP-0620500-A2 Resist and pattern formation using the same HITACHI, LTD. (JP) 1994-10-19 EP disclosed