Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.50 |
| ▸ | CASR | P41180 | 1/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9224643 | 0.99 | MEN1 (0.67) | MEN1KMT2AMAPTCYP2D6HTT | |
| SCHEMBL9410194 | 0.86 | MEN1 (0.67) | MEN1KMT2ACYP2D6ADRB2ADRB1 | |
| Hydrochloric Acid SCHEMBL9410196 | 0.85 | MEN1 (0.65) | MEN1KMT2AMAPTCYP2D6ADRB2 | |
| SCHEMBL15677156 | 0.84 | MEN1 (0.63) | MEN1KMT2AMAPTADRB2ADRB1 | |
| SCHEMBL10595635 | 0.82 | CYP2D6 (0.53) | MEN1KMT2AMAPTCYP2D6HTT | |
| SCHEMBL29266753 | 0.81 | KMT2A (0.61) | MEN1KMT2AMAPTHTTADRB2 | |
| Hydrochloric Acid SCHEMBL10593904 | 0.81 | MAPT (0.53) | MEN1KMT2AMAPTCYP2D6HTT | |
| SCHEMBL27503651 | 0.80 | ADRB2 (0.56) | MEN1KMT2AMAPTCYP2D6HTT | |
| SCHEMBL9410178 | 0.78 | KMT2A (0.74) | MEN1KMT2AMAPTADRB2CASR | |
| SCHEMBL17024118 | 0.77 | MEN1 (0.56) | MEN1KMT2AMAPTHTTADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611748-A1 | Propanolamine derivatives and their use as hypotensive or antiglaucoma agents | Senju Pharmaceutical Co., Ltd. (JP) | 1994-08-24 | — | — | EP | claimed |