Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 4/20 | 0.40 |
| ▸ | GRIK2 | Q13002 | 4/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21986677 | 0.76 | GRIK1 (0.41) | GRIK1GRIK2SLC22A6HDAC2FOLH1 | |
| SCHEMBL6329381 | 0.76 | SLC22A6 (0.52) | GRIK1GRIK2SLC22A6HDAC2TDP1 | |
| SCHEMBL6329384 | 0.76 | SLC22A6 (0.52) | GRIK1GRIK2SLC22A6HDAC2TDP1 | |
| SCHEMBL22500687 | 0.74 | GRIK1 (0.40) | GRIK1GRIK2SLC22A6HDAC2FOLH1 | |
| SCHEMBL22500689 | 0.74 | GRIK1 (0.40) | GRIK1GRIK2SLC22A6HDAC2FOLH1 | |
| SCHEMBL23241896 | 0.74 | GRIK1 (0.48) | GRIK1GRIK2SLC22A6HDAC2 | |
| SCHEMBL21986648 | 0.74 | GRIK1 (0.40) | GRIK1GRIK2SLC22A6HDAC2TDP1 | |
| SCHEMBL23241895 | 0.74 | GRIK1 (0.48) | GRIK1GRIK2SLC22A6HDAC2 | |
| SCHEMBL13351667 | 0.74 | GRIK1 (0.58) | GRIK1GRIK2SLC22A6HDAC2FOLH1 | |
| SCHEMBL9770925 | 0.74 | GRIK1 (0.48) | GRIK1GRIK2SLC22A6HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0587333-A2 | Multi-stage polymers having alkali-soluble and alkali-insoluble stages | ROHM AND HAAS COMPANY (US) | 1994-03-16 | — | — | EP | disclosed |