Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 4/20 | 0.48 |
| ▸ | GRIK2 | Q13002 | 4/20 | 0.48 |
| ▸ | GABRP | O00591 | 2/20 | 0.37 |
| ▸ | GABRD | O14764 | 2/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.37 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.37 |
| ▸ | GABRE | P78334 | 2/20 | 0.37 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.37 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.37 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.37 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.37 |
| ▸ | ANPEP | P15144 | 3/20 | 0.34 |
| ▸ | ENPEP | Q07075 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23241895 | 1.00 | GRIK1 (0.48) | GRIK1GRIK2GABRPGABRDGABRA1 | |
| SCHEMBL23241896 | 1.00 | GRIK1 (0.48) | GRIK1GRIK2GABRPGABRDGABRA1 | |
| SCHEMBL28202300 | 0.79 | GABRP (0.39) | GRIK1GRIK2GABRPGABRDGABRA1 | |
| SCHEMBL6371658 | 0.79 | GABRP (0.39) | GRIK1GRIK2GABRPGABRDGABRA1 | |
| SCHEMBL22211292 | 0.78 | GRIK1 (0.44) | GRIK1GRIK2GABRPGABRDGABRA1 | |
| SCHEMBL6329384 | 0.76 | SLC22A6 (0.52) | GRIK1GRIK2GABRR1SLC22A6HDAC2 | |
| SCHEMBL21986677 | 0.76 | GRIK1 (0.41) | GRIK1GRIK2GABRPGABRDGABRA1 | |
| SCHEMBL6329381 | 0.76 | SLC22A6 (0.52) | GRIK1GRIK2GABRR1SLC22A6HDAC2 | |
| SCHEMBL18954915 | 0.75 | GRIK1 (0.70) | GRIK1GRIK2 | |
| SCHEMBL420881 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045537-A | Treating Diseases Caused by Retroviruses | SANDOZ LTD. (CH) | 1991-09-03 | — | — | US | disclosed |