Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.35 |
| ▸ | HTR3B | O95264 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9410336 | 0.95 | TSHR (0.48) | TSHRKMT2AMEN1ARGAA | |
| SCHEMBL9410390 | 0.92 | TSHR (0.55) | TSHRKMT2AMEN1GAAMAPT | |
| SCHEMBL9410374 | 0.90 | TSHR (0.49) | TSHRKMT2AMEN1GAAMAPT | |
| SCHEMBL11179679 | 0.90 | TSHR (0.46) | TSHRKMT2AMEN1ARGAA | |
| SCHEMBL9410302 | 0.88 | TSHR (0.47) | TSHRKMT2AGAAMAPTPOLB | |
| SCHEMBL9410286 | 0.87 | KMT2A (0.54) | TSHRKMT2AMEN1GAAMAPT | |
| SCHEMBL9410320 | 0.86 | TSHR (0.48) | TSHRKMT2AMEN1GAAMAPT | |
| SCHEMBL11179609 | 0.85 | AR (0.52) | TSHRKMT2AMEN1ARGAA | |
| SCHEMBL11180464 | 0.84 | TSHR (0.57) | TSHRKMT2AMEN1GAAPOLB | |
| SCHEMBL9410354 | 0.84 | TSHR (0.57) | TSHRKMT2AMEN1GAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0583971-A1 | Piperidine derivatives | SANKYO COMPANY LIMITED (JP) | 1994-02-23 | — | — | EP | disclosed |