Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SCN1A | P35498 | 1/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11186095 | 0.95 | KMT2A (0.52) | KMT2AMEN1TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL9410265 | 0.94 | KMT2A (0.53) | KMT2AMEN1TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL9359743 | 0.91 | TSHR (0.53) | KMT2ATSHRSMN1; SMN2MAPTKDM4E | |
| SCHEMBL9410279 | 0.89 | TSHR (0.47) | KMT2AMEN1TSHRALDH1A1MAPT | |
| SCHEMBL9410264 | 0.87 | TSHR (0.48) | KMT2AMEN1TSHRALDH1A1MAPT | |
| SCHEMBL9410297 | 0.87 | TSHR (0.45) | KMT2AMEN1TSHRKDM4EMAPK1 | |
| SCHEMBL9410284 | 0.85 | ALDH1A1 (0.48) | KMT2AMEN1TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL11179679 | 0.84 | TSHR (0.46) | KMT2AMEN1TSHRALDH1A1MAPT | |
| SCHEMBL11175662 | 0.82 | TSHR (0.55) | KMT2AMEN1TSHRGAACYP2D6 | |
| SCHEMBL9410338 | 0.82 | TSHR (0.55) | KMT2AMEN1TSHRGAACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0583971-A1 | Piperidine derivatives | SANKYO COMPANY LIMITED (JP) | 1994-02-23 | — | — | EP | disclosed |