Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN7A | Q01118 | 2/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.52 |
| ▸ | DRD2 | P14416 | 2/20 | 0.50 |
| ▸ | DRD3 | P35462 | 2/20 | 0.50 |
| ▸ | STAT3 | P40763 | 4/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.48 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.47 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.47 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3056609 | 0.88 | STAT3 (0.51) | DRD2DRD3STAT3MAOAPIK3CA | |
| SCHEMBL3055660 | 0.85 | STAT3 (0.48) | DRD2DRD3STAT3MAOAMAPK1 | |
| SCHEMBL3061058 | 0.85 | STAT3 (0.48) | DRD2DRD3STAT3ALDH1A1KMT2A | |
| SCHEMBL3058681 | 0.82 | STAT3 (0.49) | STAT3 | |
| Bromide SCHEMBL3062612 | 0.81 | STAT3 (0.46) | DRD2DRD3STAT3MEN1KMT2A | |
| SCHEMBL3061136 | 0.81 | MAOA (0.48) | DRD2DRD3STAT3MAOAMAPK1 | |
| SCHEMBL3065449 | 0.80 | STAT3 (0.53) | DRD2DRD3STAT3PIK3CAPRKAA2 | |
| SCHEMBL3057622 | 0.80 | STAT3 (0.53) | DRD2DRD3STAT3PIK3CAPRKAA2 | |
| Bromide SCHEMBL3062614 | 0.80 | STAT3 (0.46) | STAT3PIK3CAPRKAA2 | |
| SCHEMBL3055087 | 0.80 | STAT3 (0.47) | STAT3MAOAPIK3CAPRKAA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0624575-A1 | Substituted indoles and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1994-11-17 | — | — | EP | disclosed |