Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 8/20 | 0.56 |
| ▸ | HTR2A | P28223 | 2/20 | 0.48 |
| ▸ | HTR2C | P28335 | 2/20 | 0.48 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.47 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15785129 | 0.87 | ACKR3 (0.52) | ACKR3HTR2AHTR2CDPP4DPP7 | |
| SCHEMBL9247297 | 0.82 | KMT2A (0.52) | HTR2AHTR2CKCNH2KMT2A | |
| SCHEMBL9411466 | 0.79 | ACKR3 (0.47) | ACKR3HTR2AHTR2CKCNH2 | |
| SCHEMBL9411469 | 0.79 | ACHE (0.65) | — | |
| Hydrochloric Acid SCHEMBL9411652 | 0.78 | ACKR3 (0.46) | ACKR3HTR2AHTR2CKCNH2 | |
| SCHEMBL13735867 | 0.78 | HDAC1 (0.51) | DPP4DPP7OPRL1KMT2A | |
| SCHEMBL1838212 | 0.78 | MEN1 (0.61) | ACKR3DPP4DPP7KMT2A | |
| SCHEMBL23344410 | 0.76 | PDK2 (0.43) | ACKR3DPP4DPP7OPRL1 | |
| SCHEMBL9411376 | 0.75 | HPGD (0.48) | KMT2A | |
| SCHEMBL9256634 | 0.74 | KMT2A (0.54) | KCNH2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0602242-A1 | BENZISOXAZOLE COMPOUND AND USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-06-22 | — | — | EP | disclosed |