Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.69 |
| ▸ | HTR4 | Q13639 | 4/20 | 0.61 |
| ▸ | DRD3 | P35462 | 3/20 | 0.56 |
| ▸ | DRD4 | P21917 | 4/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.56 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.56 |
| ▸ | ACHE | P22303 | 1/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | HTR2C | P28335 | 1/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.56 |
| ▸ | HTR2B | P41595 | 1/20 | 0.56 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.56 |
| ▸ | HTR3A | P46098 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9412933 | 1.00 | DRD2 (0.69) | DRD2HTR4DRD3DRD4CYP1A2 | |
| SCHEMBL11237366 | 0.93 | DRD2 (0.71) | DRD2HTR4DRD3DRD4CYP1A2 | |
| SCHEMBL11237369 | 0.93 | DRD2 (0.71) | DRD2HTR4DRD3DRD4CYP1A2 | |
| SCHEMBL9412905 | 0.92 | DRD2 (0.70) | DRD2HTR4DRD3DRD4CYP1A2 | |
| SCHEMBL11232514 | 0.92 | DRD2 (0.70) | DRD2HTR4DRD3DRD4CYP1A2 | |
| SCHEMBL9412901 | 0.92 | DRD2 (0.70) | DRD2HTR4DRD3DRD4CYP1A2 | |
| SCHEMBL11232518 | 0.92 | DRD2 (0.70) | DRD2HTR4DRD3DRD4CYP1A2 | |
| SCHEMBL9413082 | 0.91 | DRD2 (0.58) | DRD2HTR4DRD3DRD4CYP1A2 | |
| SCHEMBL9413072 | 0.91 | DRD2 (0.58) | DRD2HTR4DRD3DRD4CYP1A2 | |
| SCHEMBL11227150 | 0.91 | DRD2 (0.69) | DRD2HTR4DRD3DRD4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623621-A1 | Oxazabicyclo derivatives and their use as 5-HT4 receptor agonists | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1994-11-09 | — | — | EP | disclosed |