Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 5/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9414287 | 0.91 | PPARG (0.44) | DPP4PPARGOPRM1OPRK1GRIN1 | |
| SCHEMBL9414225 | 0.88 | PPARG (0.42) | DPP4PPARGOPRM1OPRK1GRIN1 | |
| SCHEMBL9414278 | 0.87 | DPP4 (0.46) | DPP4PPARGOPRM1OPRK1GRIN1 | |
| SCHEMBL9414218 | 0.87 | PPARG (0.51) | DPP4PPARGKMT2A | |
| SCHEMBL9414221 | 0.85 | DPP4 (0.43) | DPP4PPARGOPRM1OPRK1GRIN1 | |
| SCHEMBL9414242 | 0.82 | PPARG (0.44) | DPP4PPARGGRIN1GRIN2B | |
| SCHEMBL9414228 | 0.82 | PPARG (0.41) | DPP4PPARGGRIN1GRIN2B | |
| SCHEMBL9414215 | 0.82 | DPP4 (0.41) | DPP4PPARGGRIN1GRIN2B | |
| SCHEMBL9414243 | 0.81 | DPP4 (0.45) | DPP4PPARGOPRM1OPRK1GRIN1 | |
| SCHEMBL9414238 | 0.81 | ADORA2A (0.44) | DPP4PPARGGRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0589201-A1 | Di- and triazindeones | MERCK PATENT GmbH (DE) | 1994-03-30 | — | — | EP | disclosed |