SCHEMBL9414218

SCHEMBL9414218

CCCc1cc(=O)n(Cc2ccccc2)c(=O)n1Cc1ccccc1-c1ccccc1C#N

nearest known ligand 0.52

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PPARG P37231 2/20 0.51
DPP4 P27487 5/20 0.48
EGLN3 Q9H6Z9 1/20 0.41
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
HPGD P15428 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9414287 0.88 PPARG (0.44) PPARGDPP4KMT2A
SCHEMBL9414213 0.87 DPP4 (0.48) PPARGDPP4KMT2A
SCHEMBL9414278 0.86 DPP4 (0.46) PPARGDPP4KMT2A
SCHEMBL9414221 0.86 DPP4 (0.43) PPARGDPP4HPGD
SCHEMBL9414242 0.85 PPARG (0.44) PPARGDPP4
SCHEMBL9414225 0.85 PPARG (0.42) PPARGDPP4KMT2A
SCHEMBL9414238 0.84 ADORA2A (0.44) PPARGDPP4
SCHEMBL9414228 0.83 PPARG (0.41) PPARGDPP4
SCHEMBL9414215 0.83 DPP4 (0.41) PPARGDPP4
SCHEMBL9414249 0.82 PPARG (0.37) PPARGDPP4EGLN3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0589201-A1 Di- and triazindeones MERCK PATENT GmbH (DE) 1994-03-30 EP disclosed