Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9414237 | 0.90 | AGTR1 (0.34) | KDM4E | |
| SCHEMBL8539427 | 0.88 | AGTR1 (0.42) | — | |
| SCHEMBL9414266 | 0.88 | AGTR1 (0.33) | — | |
| SCHEMBL9414231 | 0.85 | PPARG (0.38) | KMT2AMEN1CYP2C9CYP2C19HSD17B10 | |
| SCHEMBL9414205 | 0.85 | AGTR1 (0.35) | — | |
| SCHEMBL9414259 | 0.85 | HPGD (0.35) | — | |
| SCHEMBL9414217 | 0.84 | AGTR1 (0.34) | — | |
| SCHEMBL9414234 | 0.83 | GAA (0.31) | CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL9414216 | 0.81 | AGTR1 (0.32) | — | |
| SCHEMBL8541171 | 0.81 | AGTR1 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0589201-A1 | Di- and triazindeones | MERCK PATENT GmbH (DE) | 1994-03-30 | — | — | EP | disclosed |