Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INPP5A | Q14642 | 2/20 | 0.71 |
| ▸ | ITPR3 | Q14573 | 8/20 | 0.56 |
| ▸ | ITPR2 | Q14571 | 4/20 | 0.56 |
| ▸ | ITPR1 | Q14643 | 4/20 | 0.56 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.56 |
| ▸ | AKT1 | P31749 | 1/20 | 0.56 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10344992 | 0.97 | INPP5A (0.67) | INPP5AITPR3ITPR2ITPR1INPPL1 | |
| SCHEMBL4456065 | 0.94 | INPP5A (0.78) | INPP5AITPR3ITPR2ITPR1INPPL1 | |
| SCHEMBL8460802 | 0.94 | INPP5A (0.78) | INPP5AITPR3ITPR2ITPR1INPPL1 | |
| SCHEMBL10345051 | 0.92 | INPP5A (0.67) | INPP5AITPR3ITPR2ITPR1INPPL1 | |
| SCHEMBL9414301 | 0.89 | INPP5A (0.71) | INPP5AITPR3ITPR2ITPR1INPPL1 | |
| SCHEMBL9414291 | 0.89 | INPP5A (0.71) | INPP5AITPR3ITPR2ITPR1INPPL1 | |
| SCHEMBL9414284 | 0.88 | INPP5A (0.70) | INPP5AITPR3ITPR2ITPR1INPPL1 | |
| SCHEMBL10345151 | 0.86 | INPP5A (0.67) | INPP5AITPR3ITPR2ITPR1INPPL1 | |
| SCHEMBL1403803 | 0.86 | INPP5A (0.67) | INPP5AITPR3ITPR2ITPR1INPPL1 | |
| SCHEMBL10344635 | 0.85 | INPP5A (0.50) | INPP5AITPR3ITPR2ITPR1INPPL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579957-A1 | Preparation of isomers of myoinositol derivatives | 3i RESEARCH EXPLOITATION LIMITED (GB) | 1994-01-26 | — | — | EP | claimed |
| EP-0354904-A1 | INOSITOL PHOSPHATE ANALOGUES | 3i RESEARCH EXPLOITATION LIMITED (GB) | 1990-02-21 | — | — | EP | claimed |
| WO-1988007047-A1 | INOSITOL PHOSPHATE ANALOGUES | RESEARCH CORPORATION LIMITED (GB) | 1988-09-22 | — | — | WO | claimed |
| EP-0579957-A1 | Preparation of isomers of myoinositol derivatives | 3i RESEARCH EXPLOITATION LIMITED (GB) | 1994-01-26 | — | — | EP | disclosed |
| EP-0354904-A1 | INOSITOL PHOSPHATE ANALOGUES | 3i RESEARCH EXPLOITATION LIMITED (GB) | 1990-02-21 | — | — | EP | disclosed |
| WO-1988007047-A1 | INOSITOL PHOSPHATE ANALOGUES | RESEARCH CORPORATION LIMITED (GB) | 1988-09-22 | — | — | WO | disclosed |