Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB1 | P20618 | 9/20 | 0.60 |
| ▸ | PSMB5 | P28074 | 8/20 | 0.60 |
| ▸ | ESR1 | P03372 | 7/20 | 0.60 |
| ▸ | PSMB2 | P49721 | 3/20 | 0.60 |
| ▸ | PDE1A | P54750 | 4/20 | 0.55 |
| ▸ | PDE1B | Q01064 | 4/20 | 0.55 |
| ▸ | PDE1C | Q14123 | 4/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9414739 | 1.00 | PSMB1 (0.60) | PSMB1PSMB5ESR1PSMB2PDE1A | |
| SCHEMBL9415631 | 0.90 | PSMB1 (0.74) | PSMB1PSMB5ESR1PSMB2PDE1A | |
| SCHEMBL9415307 | 0.90 | ESR1 (0.62) | PSMB1PSMB5ESR1PSMB2PDE1A | |
| SCHEMBL9415300 | 0.90 | ESR1 (0.62) | PSMB1PSMB5ESR1PSMB2PDE1A | |
| SCHEMBL9415633 | 0.90 | PSMB1 (0.74) | PSMB1PSMB5ESR1PSMB2PDE1A | |
| SCHEMBL9415443 | 0.89 | ESR1 (0.62) | PSMB1PSMB5ESR1PSMB2PDE1A | |
| SCHEMBL9415440 | 0.89 | ESR1 (0.62) | PSMB1PSMB5ESR1PSMB2PDE1A | |
| SCHEMBL9414855 | 0.88 | CTNNB1 (0.46) | — | |
| SCHEMBL9415574 | 0.88 | PSMB1 (0.59) | PSMB1PSMB5ESR1PSMB2PDE1A | |
| SCHEMBL9415575 | 0.88 | PSMB1 (0.59) | PSMB1PSMB5ESR1PSMB2PDE1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0589039-A1 | TRIPHENYLETHYLENE DERIVATIVE AND PHARMACEUTICAL PREPARATION CONTAINING THE SAME | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1994-03-30 | — | — | EP | disclosed |