Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 3/20 | 0.57 |
| ▸ | CTSB | P07858 | 3/20 | 0.52 |
| ▸ | CTSK | P43235 | 3/20 | 0.52 |
| ▸ | CTSL | P07711 | 2/20 | 0.52 |
| ▸ | CCR1 | P32246 | 2/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 2/20 | 0.46 |
| ▸ | PREP | P48147 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13928545 | 0.90 | PREP (0.56) | CAPN1PREPALDH1A1CYP1A2 | |
| SCHEMBL13950861 | 0.90 | PREP (0.56) | CAPN1PREPALDH1A1CYP1A2 | |
| SCHEMBL22798286 | 0.89 | CAPN1 (0.61) | CAPN1CTSBCTSKCTSLCCR1 | |
| SCHEMBL18619560 | 0.89 | CAPN1 (0.61) | CAPN1CTSBCTSKCTSLCCR1 | |
| SCHEMBL18619561 | 0.89 | CAPN1 (0.61) | CAPN1CTSBCTSKCTSLCCR1 | |
| SCHEMBL22798219 | 0.89 | CAPN1 (0.61) | CAPN1CTSBCTSKCTSLCCR1 | |
| SCHEMBL1506251 | 0.81 | ACE (0.61) | CAPN1CTSBCTSKCTSLCCR1 | |
| SCHEMBL10063674 | 0.81 | ACE (0.61) | CAPN1CTSBCTSKCTSLCCR1 | |
| SCHEMBL15746341 | 0.81 | PIN1 (0.46) | CYP1A2 | |
| SCHEMBL15692966 | 0.81 | PIN1 (0.46) | CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0618223-A2 | Peptides inhibiting interleukin 1-bêta release useful as antiinflammatory agents | SANDOZ LTD. (CH) | 1994-10-05 | — | — | EP | disclosed |