Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | STAT1 | P42224 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9415887 | 0.85 | DHODH (0.43) | DHODHGAALMNACYP3A4CYP2D6 | |
| SCHEMBL9415878 | 0.85 | GAA (0.43) | DHODHGAALMNACYP3A4CYP2D6 | |
| SCHEMBL9415872 | 0.85 | DHODH (0.43) | DHODHGAALMNACYP3A4CYP2D6 | |
| SCHEMBL9415883 | 0.83 | DHODH (0.47) | DHODHLMNACYP3A4CYP2D6KDM4E | |
| SCHEMBL9415865 | 0.82 | DHODH (0.49) | DHODHGAALMNACYP3A4CYP2D6 | |
| SCHEMBL8123710 | 0.77 | MEN1 (0.46) | DHODHGAALMNACYP3A4CYP2D6 | |
| SCHEMBL8123707 | 0.77 | MEN1 (0.46) | DHODHGAALMNACYP3A4CYP2D6 | |
| SCHEMBL20912581 | 0.76 | MEN1 (0.45) | DHODHGAALMNACYP3A4CYP2D6 | |
| SCHEMBL20912579 | 0.76 | MEN1 (0.45) | DHODHGAALMNACYP3A4CYP2D6 | |
| SCHEMBL19728782 | 0.76 | MEN1 (0.45) | DHODHGAALMNACYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0612731-A1 | Novel guinolone and naphthyridone derivatives | BAYER AG (DE) | 1994-08-31 | — | — | EP | disclosed |